Postdoctoral and PhD student positions in skeletal muscle plasticity (100%, funded)
(group of Prof. Christoph Handschin, Biozentrum/University of Basel)
The Biozentrum of the University of Basel is one of the leading life sciences institutes in the world. It consists of 30 groups and 500 employees that research how molecules and cells create life, spanning the scale from atom to organism. Founded in 1971, the Biozentrum has been the birth place of many fundamental discoveries in biology and medicine, spawning several Nobel Laureates.
In an interdisciplinary project supported by a Sinergia grant of the Swiss National Science Foundation, we will investigate the molecular underpinnings of gene regulation in muscle plasticity. Thus, in close collaboration with the group of Prof. Sebastian Hiller, comprehensive analysis of RNA-binding, liquid-liquid phase separated condensate formation of transcriptional regulators, coupled to the elucidation of the corresponding structure-function aspects will be performed using various state-of-the-art technologies, spanning from molecular biology to animal (patho) physiology. We are therefore looking for a motivated and well-trained PhD and Postdoc to join the multidisciplinary team of postdocs and PhD students from the Handschin and Hiller groups performing these studies in close collaboration and constant exchange.
Postdoctoral applicants should have a PhD or MD/PhD, PhD student applicants a MSc or equivalent degree. A strong background in molecular and cell biology is required. Experience in RNA-binding protein biology, liquid-liquid phase separation, NGS-based techniques and analysis (e.g. CLIP or ChIPseq), or proteomics of protein complexes and PTMs is ideal. Selection will furthermore be based on the educational background, motivation, independence and creativity of the applicant. Good knowledge of English is a requirement. The positions are funded and salaries according to institutional guidelines.
We offer you
Our international team consists of a dynamic and collaborative group of scientists, committed to work at the frontier of science and to solve fundamental questions about muscle plasticity. Successful applicants will be embedded at the interface of the Handschin and Hiller groups. The Biozentrum provides a highly stimulating collaborative research environment with a fantastic infrastructure in a brand-new building. Further, we have access to state-of-the-art technology platforms providing the lab with an optimal environment for carrying out cutting-edge interdisciplinary research.
Basel is an international city with people from 150 nations. Located on the border where three countries meet - Switzerland-Germany- France -, it is Europe's most important life sciences hub. Basel provides a high standard of living and a rich and varied cultural atmosphere.
Application / Contact
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