100%, Start in October 2022
A postdoc position is available in the laboratory of Professor Momo Bentires-Alj (https://bentireslab.org/) at the Department of Biomedicine (DBM) in Basel, Switzerland. The successful candidate will work on primary cancer tissue and use a variety of single cell OMICs to assess mechanisms of action of immunotherapy.
Selected publications of our lab include: 1- PIK3CAH1047R induces multipotency and multi-lineage mammary tumors. Koren S, et al., Nature 2015. 2- Hippo kinases LATS1/2 control human breast cell fate via crosstalk with ERα. Britschgi A, et al., Nature 2017. 3. Glucocorticoids promote breast cancer metastasis. Obradović MMS, et al. Nature 2019. 4. Hepatic stellate cells suppress NK cell sustained breast cancer dormancy. Correia AL, et al., Nature 2021.
The successful candidate will work on molecular and cellular mechanisms underlying cancer response to immunotherapy using patient tissue and derived organoids, heterotypic cultures, humanized mouse models, and a variety of single cell OMICs and molecular and cellular biology approaches.
A strong experience in immunology. Expertise in single cell OMICs, 3D heterotypic cultures, and/or mouse work is a plus. The candidate should be well-organized, highly motivated, a team player, and must be fluent in English.
We offer you
A stimulating, challenging and interdisciplinary translational research environment, state-of-the-art technologies and core facilities, and attractive employment conditions. The DBM is an international institute pursuing basic, translational and clinical research, with access to cutting-edge core facilities.
Lab website: https://bentireslab.org/.